beta4-TAT is a kind of beta-sheet peptide foldamer. beta4-TAT is composed of two parts: the beta4 sequence (derived from the beta-sheet fragment of the RRM domain of fused in sarcoma (FUS)) and the TAT sequence (a nuclear localization signal peptide that helps the entire peptide penetrate the nuclear membrane). beta4-TAT influences FUS aggregation by targeting its RNA recognition motifs (RRM). beta4-TAT effectively induces FUS aggregation within cells, leading to the death of cancer cells. beta4-TAT can be used for the study of FUS[1].
Molecular Weight:
2205.62
CAS Number:
[2780353-11-7]
Formula:
C96H169N39O21
Target:
Others
Application Notes:
MCE Product type: Peptides
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