Cortistatin-8 (CST-8, PCFWKTCK), a neuropeptide, is a GHS-R1a antagonist by counteracting the response of ghrelin on gastric acid secretion. Cortistatin-8 can modulate GH release from somatotroph cells. Cortistatin-8 is a synthetic CST-analogue devoid of any binding affinity to SST-R but capable to bind the GHS-R1a. Cortistatin-8 can exert antagonistic effects on ghrelin actions either in vitro or in vivo in animals[1].
Molecular Weight:
1009.25
Purity:
98.86
CAS Number:
[485803-62-1]
Formula:
C47H68N12O9S2
Target:
GHSR
Application Notes:
MCE Product type: Reference compound
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