Tachyplesin II is a broad-spectrum cationic antimicrobial peptide. Tachyplesin II has significant inhibitory effects on Gram-positive bacteria, Gram-negative bacteria, and some fungi. Tachyplesin II binds to bacterial membrane lipopolysaccharides through its positive charge, disrupting membrane integrity and causing leakage of cellular contents. Tachyplesin II can bind to DNA grooves, inhibiting microbial replication, and also suppressing HIV-1 replication and the proliferation of liver cancer cells[1].
Molecular Weight:
2264.73
Formula:
C99H150N34O20S4
Target:
Bacterial,DNA Alkylator/Crosslinker,Fungal,HIV
Application Notes:
MCE Product type: Peptides
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