SGNLTKYWKKIWKPGIKKWIK is a thymidylate kinase (TMK)-targeting antimicrobial peptide with a KD value of 4.721 µM. SGNLTKYWKKIWKPGIKKWIK exerts antimicrobial effects through multiple mechanisms, including membrane disruption, induction of ROS, and DNA binding. SGNLTKYWKKIWKPGIKKWIK shows remarkable activity against Gram-negative bacteria, possesses good biocompatibility, and rarely induces drug resistance. SGNLTKYWKKIWKPGIKKWIK can be used for research on Gram-negative bacterial infections[1].
Molecular Weight:
2603.16
Formula:
C128H200N32O26
Target:
Bacterial,DNA/RNA Synthesis,Interleukin Related,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Peptides
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