CPO_Abeta17-21P is a apoE/Abeta interaction inhibitor with an IC50 of 1.02 nM. CPO_Abeta17-21P significantly inhibits ApoE4-mediated aggregation of Abeta40 and Abeta42. CPO_Abeta17-21P significantly improves cognitive function and comprehensively alleviates Alzheimers disease (AD)-related pathologies in mouse models. CPO_Abeta17-21P is applicable to the research of AD[1].
Molecular Weight:
703.83
Formula:
C37H49N7O7
Application Notes:
MCE Product type: Peptides
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