LBP-14, a peptide, is a synthetic fragment of the LPS (HY-D1056) binding protein (LBP) and is a LPS antagonist. LBP-14 interacts with LPS via electrostatic contacts between arginine/lysine residues and LPS phosphate groups, and hydrophobic contacts between aromatic/aliphatic residues and LPS acyl chains, blocking LPS binding to LBP. LBP-14 moderately inhibits LPS-induced TNF-alpha formation. LBP-14 can be used for the research of gram-negative sepsis[1].
Molecular Weight:
1765.07
CAS Number:
[324030-22-0]
Formula:
C82H129N27O17
Target:
Bacterial
Application Notes:
MCE Product type: Reference compound
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