Cyclotraxin B TFA is a BBB-penetrable and selective TrkB inhibitor. Cyclotraxin B TFA inhibits BDNF-induced TrkB activity in a non-competitive manner, with an IC50 of 0.30 nM. Cyclotraxin B TFA has analgesic and anxiolytic effects[1][2][3].
Molecular Weight:
1314.39
Formula:
C50H74F3N13O19S3
Target:
Trk Receptor
Application Notes:
MCE Product type: Peptides
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