Pam2CSK4, a lipopeptide, is a TLR6-independent TLR2 ligand and agonist. Pam2CSK4 promotes platelet aggregation, and increases platelet adhesion to collagen-coated surfaces in a TLR2/NF-kappaB/BTK-dependent manner. Pam2CSK4 also activates iNOS expression and NO production in mouse macrophages[1][2][3].
Molecular Weight:
1271.82
CAS Number:
[868247-72-7]
Formula:
C65H126N10O12S
Target:
Toll-like Receptor (TLR)
Application Notes:
MCE Product type: Peptides
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