Pam2CSK4 (TFA), a lipopeptide, is a TLR6-independent TLR2 ligand and agonist. Pam2CSK4 (TFA) promotes platelet aggregation, and increases platelet adhesion to collagen-coated surfaces in a TLR2/NF-kappaB/BTK-dependent manner. Pam2CSK4 (TFA) also activates iNOS expression and NO production in mouse macrophages[1][2][3].
Molecular Weight:
1271.82 (free base)
Purity:
99.46
Formula:
C65H126N10O12S.xC2HF3O2
Target:
Toll-like Receptor (TLR)
Application Notes:
Peptides
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