BAM(8-22), a proteolytically cleaved product of proenkephalin A and sensory neuron-specific receptor (SNSR) agonist, is a potent activator of Mas-related G-protein-coupled receptors (Mrgprs), MrgprC11 and hMrgprX1. BAM(8-22) induces scratching in mice in an Mrgpr-dependent manner. In addition, BAM(8-22) has an analgesic effect and can also inhibit the activation of microglia[1][2][3][4].
Molecular Weight:
1971.20
Purity:
99.86
CAS Number:
[412961-36-5]
Formula:
C91H127N25O23S
Target:
Mas-related G-protein-coupled Receptor (MRGPR)
Application Notes:
MCE Product type: Peptides
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