PKI 14-22 amide,myristoylated, CAS [[201422-03-9]]
Biozol Catalog Number:
MCE-HY-P1291
Supplier Catalog Number:
HY-P1291
Alternative Catalog Number:
MCE-HY-P1291-1MG,MCE-HY-P1291-5MG
Manufacturer:
MedchemExpress
Category:
Proteine/Peptide
PKI 14-22 amide, myristoylated is a selective, cAMP-dependent, competitive PKA inhibitor with Ki=~36 nM. The myristoylation modification of PKI 14-22 amide, myristoylated makes it more permeable to cell membranes and blood-brain barriers than the precursor molecule. PKI 14-22 amide, myristoylated can block the phosphorylation of cAMP-dependent downstream targets (such as CREB). PKI 14-22 amide, myristoylated can prevent the development of morphine analgesic tolerance in mice, and also inhibits protein translation and negative-strand RNA synthesis of Zika virus. PKI 14-22 amide, myristoylated can be used in research fields such as opioid tolerance mechanisms and antiviral drugs[1][2][3].
Molecular Weight:
1209.49
Purity:
99.65
CAS Number:
[201422-03-9]
Formula:
C53H100N20O12
Target:
Epigenetic Reader Domain,Flavivirus,PKA
Application Notes:
MCE Product type: Peptides
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