D15, a peptide with 15 aa segment of dynamin, is an AMPAR endocytosis inhibitor. D15 blocks the interaction of dynamin with amphiphysin 1 and 2. D15 significantly increases AMPAR excitatory postsynaptic potential (EPSC) amplitude of medium spiny neurons (MSNs) in Sapap3 KO mice. D15 can be used for neuropsychiatric disorder research[1].
Molecular Weight:
1566.76
CAS Number:
[251939-41-0]
Formula:
C69H111N23O19
Target:
iGluR
Application Notes:
MCE Product type: Peptides
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