GsMTx4 is a spider venom peptide that selectively inhibits cationic-permeable mechanosensitive channels (MSCs) belonging to the Piezo and TRP channel families. GsMTx4 also blocks cation-selective stretch-activated channels (SACs) , attenuates lysophosphatidylcholine (LPC)-induced astrocyte toxicity and microglial reactivity. GsMTx4 is an important pharmacological tool for identifying the role of these excitatory MSCs in normal physiology and pathology[1][2][4].
Molecular Weight:
4095.84
Purity:
99.83
CAS Number:
[1209500-46-8]
Formula:
C185H273N49O45S6
Target:
Piezo Channel,TRP Channel
Application Notes:
MCE Product type: Peptides
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