D-GsMTx4 is a spider peptide and the D enantiomer of GsMTx4 (HY-P1410). D-GsMTx4 inhibits the mechanosensitive ion channel Piezo2. D-GsMTx4 inhibits [Ca2+]i elevation. D-GsMTx4 inhibits mTOR and PI3K-Akt signaling pathways. D-GsMTx4 inhibits mechanical allodynia and thermal hyperalgesia. D-GsMTx4 can be used in researches of mechanical stress, chronic pain and idiopathic pulmonary fibrosis[1][2][3][4].
Molecular Weight:
4095.84
Purity:
99.59
Formula:
C185H273N49O45S6
Target:
Akt,Calcium Channel,mTOR,PI3K,Piezo Channel
Application Notes:
MCE Product type: Peptides
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