D-GsMTx4 TFA is a spider peptide and the D enantiomer of GsMTx4 (HY-P1410). D-GsMTx4 TFA inhibits the mechanosensitive ion channel Piezo2. D-GsMTx4 TFA inhibits [Ca2+]i elevation. D-GsMTx4 TFA inhibits mTOR and PI3K-Akt signaling pathways. D-GsMTx4 TFA inhibits mechanical allodynia and thermal hyperalgesia. D-GsMTx4 TFA can be used in researches of mechanical stress, chronic pain and idiopathic pulmonary fibrosis[1][2][3][4].
Molecular Weight:
4095.84 (free base)
Purity:
99.89
Formula:
C185H273N49O45S6.xC2HF3O2
Target:
Akt,Calcium Channel,mTOR,PI3K,Piezo Channel
Application Notes:
Peptides
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