Foxy-5, a WNT5A agonist, is a mimicking peptide of WNT5A which is a non-canonical member of the Wnt family. Foxy-5 triggers cytosolic free calcium signaling without affecting beta-catenin activation and it impairs the migration and invasion of epithelial cancer cells. Foxy-5 effectively reduces the metastatic spread of WNT5A-low prostate cancer cells in an orthotopic mouse model[1][2][3].
Molecular Weight:
694.77
Purity:
99.56
CAS Number:
[881188-51-8]
Formula:
C26H42N6O12S2
Target:
Wnt
Application Notes:
Peptides
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