AP 811 acetate is a selective atrial natriuretic peptide clearance receptor (ANP-CR, NPR3) antagonist with a Ki of 0.48 nM. AP 811 acetate displays >20000-fold selectivity for NPR3 over NPR1. AP 811 acetate abolishes ANP-induced pump stimulation[1][2].
Formula:
C46H66N12O8.xC2H4O2
Target:
Endothelin Receptor
Application Notes:
Peptides
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