TAT-cyclo-CLLFVY TFA is a cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells. TAT-cyclo-CLLFVY TFA disrupts HIF-1alpha/HIF-1beta protein-protein interaction with an IC50 of 1.3 µM[1].
Molecular Weight:
2559.08 (free acid)
Formula:
C111H188N42O24S2.xC2HF3O2
Target:
HIF/HIF Prolyl-Hydroxylase
Application Notes:
Peptides
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