Spadin, a natural peptide derived from a propeptide released in blood, is a potent TREK-1 channel blocker with IC50 value of 10 nM. Spadin enhances dorsal raphe nucleus 5-HT neurotransmission in mice and induces hippocampal CREB activation and neurogenesis. Spadin can be used for antidepressant research[1][2].
Molecular Weight:
2012.34
Purity:
99.08
CAS Number:
[1270083-24-3]
Formula:
C96H142N26O22
Target:
5-HT Receptor,Potassium Channel
Application Notes:
Peptides
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