Lei-Dab7 TFA is a high affinity, selective KCa2.2 (SK2) channel blocker (Kd=3.8 nM). Lei-Dab7 TFA exhibits >200-fold selectivity for KCa2.2 over KCa2.1, KCa2.3, KCa3.1, Kv and Kir2.1. Lei-Dab7 TFA increases theta-burst responses and increases LTP in rat hippocampal slices in vitro.
Molecular Weight:
3392.06 (free base)
Purity:
99.75
Formula:
C141H236N46O39S6.xC2HF3O2
Target:
Potassium Channel
Application Notes:
Peptides
* VAT and and shipping costs not included. Errors and price changes excepted