ATX-II TFA is a selective sodium channel modulator toxin. ATX-II TFA enhances late sodium current, prevents full sodium channel inactivation, and generates persistent current fractions. ATX-II TFA has pro-arrhythmic effect. ATX-II TFA slows intrinsic heart rate, prolongs QT interval and sinus node recovery time, and causes sinus pauses and arrests. ATX-II TFA can be used for the research of atrial fibrillation, long QT syndrome, and long QT3 syndrome[1][2][4].
Molecular Weight:
4934.62 (free acid)
Purity:
99.65
Formula:
C213H323N63O61S6.xC2HF3O2
Target:
Sodium Channel
Application Notes:
MCE Product type: Peptides
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