InsB (9-23) is an HLA-DQ8-restricted insulin B-chain peptide composed of amino acid residues 9-23. InsB (9-23) serves as a major MHC II class-restricted antigen. InsB (9-23) supports the recognition and activation of T cells, stimulates the secretion of IFN-gamma and cytokines, and induces cross-reactive immune responses. InsB (9-23)-specific CD4 T cells can initiate diabetes. InsB (9-23) can be used in research related to type 1 diabetes and autoimmune diabetes[1][2][3].
Molecular Weight:
1645.90
Purity:
98.98
CAS Number:
[163364-16-7]
Formula:
C72H116N20O22S1
Target:
IFNAR,Insulin Receptor,MHC
Application Notes:
MCE Product type: Peptides
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