Humanin, an anti-apoptotic peptide of 24 amino acids, is a Bax inhibitor. Humanin prevents the translocation of Bax from cytosol to mitochondria, blocks Bax from the inactive to active conformation. Humanin is a mitochondria-associated peptide with a neuroprotective effect against AD-related neurotoxicity. Humanin also improves overall insulin sensitivity in animal. Humanin are related to aging[1][2]. Humanin analogue, in which the serine at position 14 is replaced by glycine, names HNG[2].
Molecular Weight:
2687.23
Purity:
99.83
CAS Number:
[330936-69-1]
Formula:
C119H204N34O32S2
Target:
Bcl-2 Family
Application Notes:
MCE Product type: Peptides
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