Elabela(19-32) is an active fragment of ELABELA (ELA) that binds to apelin receptor (APJ). Elabela(19-32) activates the Galphai1 and beta-arrestin-2 signaling pathways with EC50s of 8.6 nM and 166 nM. Elabela(19-32) induces receptor internalization and reduces arterial pressure, exerts positive inotropic effects on the heart[1].
Molecular Weight:
1707.03
Purity:
99.64
CAS Number:
[1886973-05-2]
Formula:
C75H119N25O17S2
Target:
Apelin Receptor (APJ),Arrestin
Application Notes:
Peptides
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