Tat-beclin 1, a peptide derived from a region of the autophagy protein (beclin 1), is a potent inducer of autophagy and interacts with negative regulator of autophagy, GAPR-1 (GLIPR2). Tat-beclin 1 decreases the accumulation of polyglutamine expansion protein aggregates and the replication of several pathogens (including HIV-1) in vitro, and reduces mortality in mice infected with chikungunya (CHIKV) or West Nile virus (WNV)[1].
Molecular Weight:
3741.10
Purity:
99.89
CAS Number:
[1423821-88-8]
Formula:
C164H251N57O45
Target:
Autophagy,CHIKV,HIV
Application Notes:
MCE Product type: Peptides
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