BMSpep-57 hydrochloride is a potent and competitive macrocyclic peptide inhibitor of PD-1/PD-L1 interaction with an IC50 of 7.68 nM. BMSpep-57 hydrochloride binds to PD-L1 with Kds of 19 nM and 19.88 nM in MST and SPR assays, respectively. BMSpep-57 hydrochloride facilitates T cell function by in creasing IL-2 production in PBMCs[1].
Molecular Weight:
1904.63
Purity:
99.69
Formula:
C89H127ClN24O19S
Target:
PD-1/PD-L1
Application Notes:
MCE Product type: Peptides
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