Astin B is a orally active and potent cyclic pentapeptide, that can be isolated from Aster tataricus. Astin B has hepatotoxic effects in vitro and in vivo and that hepatic injury was primarily mediated by apoptosis in a mitochondria/caspase-dependent manner. Astin B induces autophagy in L-02 cells, increases LC3-II and decreases p62 expression[1].
Molecular Weight:
586.46
CAS Number:
[151201-76-2]
Formula:
C25H33Cl2N5O7
Target:
Apoptosis,Atg8/LC3,Autophagy,Bcl-2 Family,Caspase,JNK,p62,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Natural Products
* VAT and and shipping costs not included. Errors and price changes excepted
