AY254 is an analogue of AY77 (HY-138951). AY254 is ERK-biased PAR2 agonist with an EC50 of 2 nM. AY254 relieves cytokine-induced caspase 3/8 activation. AY254 also promotes scratch-wound healing and induced IL-8 secretion via PAR2-ERK1/2 signaling[1]
Molecular Weight:
631.77
CAS Number:
[2093408-03-6]
Formula:
C30H49N9O6
Target:
Protease Activated Receptor (PAR)
Application Notes:
MCE Product type: Peptides
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