Calciseptine, CAS [[178805-91-9]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-P3269
Supplier Catalog Number:
HY-P3269
Alternative Catalog Number:
MCE-HY-P3269-1UNIT
Manufacturer:
MedchemExpress
Category:
Proteine/Peptide
Calciseptine is a natural polypeptide toxin found in the venom of the black mamba snake (Dendroaspis p. polylepis). Calciseptine is a highly effective and selective blocker of the L-type channel of the Cav1.2 subtype, with an IC50 value of 92 nM. Calciseptine has no effect on Cav3.1, Cav2.2, Cav2.1, Cav1.1, voltage-sensitive sodium channels and potassium channels. Calciseptine exhibits negative inotropic and negative relaxant effects on mice, and does not affect heart rate or the action potential of sinoatrial node pacemaker cells. Calciseptine can be used for research on cardiovascular diseases[1].
Molecular Weight:
7036.12
CAS Number:
[178805-91-9]
Formula:
C299H468N90O87S10
Target:
Calcium Channel
Application Notes:
MCE Product type: Peptides
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