OSK-1 is a potent Kv channel blocker with IC50s of of 0.6 nM, 5.4 nM, 0.014 nM for Kv1.1, Kv1.2 and Kv1.3, respectively. OSK1 is a moderate blocker of Ca2+-activated KCa3.1 channel with an IC50 of 225 nM. OSK-1 belongs to alpha-KTx3 toxins and is used as a immunosuppressive agent[1].
Molecular Weight:
4205.17
CAS Number:
[183815-75-0]
Formula:
C177H300N56O46S8
Target:
Potassium Channel
Application Notes:
MCE Product type: Peptides
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