Anrikefon (HSK21542) acetate is a peripherally restricted kappa-opioid receptor (KOR) agonist with an IC50 of 0.54 nM, an EC50 of 2.41 pM, and a Kₐ of 0.068 nM against human KOR, and it shows high selectivity over µ and delta opioid receptors. Anrikefon exerts analgesic effects by inhibiting behavioral responses associated with inflammatory, postoperative and neuropathic pain, and also exerts antipruritic effects by reducing itch-related behaviors. Anrikefon acetate can be used in the research of pain, pruritus, and pruritus associated with chronic kidney disease[1][2].
Molecular Weight:
763.97
Purity:
99.68
CAS Number:
[2584931-05-3]
Formula:
C41H61N7O7
Target:
Opioid Receptor
Application Notes:
MCE Product type: Peptides
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