(Glu2)-TRH, a metabolically stable analogue of Thyrotropin-releasing hormone (TRH, HY-P0002), is a negative modulator for the cholinergic effect of TRH in the mouse brain. (Glu2)-TRH significantly attenuates TRH-induced hippocampal extracellular acetylcholine release. (Glu2)-TRH is not metabolized by thyroliberinase. (Glu2)-TRH manifests neuroprotective, antidepressant, anticonvulsant in the CNS[1].
Molecular Weight:
354.36
Purity:
99.96
CAS Number:
[85541-78-2]
Formula:
C15H22N4O6
Target:
Endogenous Metabolite,Thyroid Hormone Receptor
Application Notes:
MCE Product type: Peptides
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