ProTx-III is a selective and potent inhibitor of voltage-gated sodium channel Nav1.7, with an IC50 of 2.1 nM. ProTx-III is a spider venom peptide isolated from the venom of the Peruvian green velvet tarantella. ProTx-III has a typical inhibitor cystine knot motif (ICK). ProTx-III is able to reverse the pain response. ProTx-III can be used to study diseases such as chronic pain, epilepsy, and arrhythmia[1].
Molecular Weight:
3802.40
CAS Number:
[1808297-63-3]
Formula:
C162H246N52O43S6
Target:
Sodium Channel
Application Notes:
MCE Product type: Peptides
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