Bid BH3 (80-99) acetate is a biological active peptide. (BID is a pro-apoptotic member of the BH3-only (BOPS) subset of the BCL-2 family of proteins that constitute a critical control point in apoptosis. Bid is the first of the BOPs reported to bind and activate Bcl-2, Bax, and Bak. Bid serves as a death-inducing ligand that moves from the cytosol to the mitochondrial membrane to inactivate Bcl-2 or to activate Bax.Pyroglutamyl (pGlu) peptides may spontaneously form when either Glutamine (Q) or Glutamic acid (E) is located at the sequence N-terminus. The conversion of Q or E to pGlu is a natural occurrence and in general it is believed that the hydrophobic gamma-lactam ring of pGlu may play a role in peptide stability against gastrointestinal proteases. Pyroglutamyl peptides are therefore considered a normal subset of such peptides and are included as part of the peptide purity during HPLC analysis.)
Molecular Weight:
2309.56 (free base)
Purity:
98.13
Formula:
C95H161N33O32S.xC2H4O2
Target:
Bcl-2 Family
Application Notes:
MCE Product type: Peptides
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