r8 Bid BH3 is a biological active peptide. (The Bid BH3 is a pro-apoptotic member of the BH3-only subset of BCL-2 family proteins that constitute a critical control point in apoptosis. r8BIDBH3 is lethal to human leukemia cell lines that expresse Bcl-2. The Bcl-2 antagonists may have the potential to be efficacious in cancer therapy. Poly-D-arginine (d-isomer as denoted by rrrrrrrr) is fused to the Bid BH3 peptide to facilitate cellular uptake of the peptide.)
Molecular Weight:
3616.10
Formula:
C145H260N66O41S
Target:
Bcl-2 Family
Application Notes:
MCE Product type: Peptides
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