TAT-M2NX (tatM2NX) is a selective inhibitor targeting human TRPM2 channels and exerts inhibitory effects on ischemic stroke. TAT-M2NX reduces H2O2-induced calcium influx via TRPM2 channels. After traumatic brain injury in mice, TAT-M2NX preserves hippocampal long-term potentiation, improves memory function, and reduces infarct volume after middle cerebral artery occlusion, but it shows no effect on female mice. TAT-M2NX can be used in studies related to traumatic brain injury and ischemic stroke[1][2].
Molecular Weight:
4354.11
Purity:
99.55
CAS Number:
[2126166-03-6]
Formula:
C190H323N71O45S
Target:
TRP Channel
Application Notes:
MCE Product type: Peptides
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