Animal-Free BMP-8a, Human (His)

Product Overview

• Article Name: Animal-Free BMP-8a, Human (His)
• Biozol Catalog Number: MCE-HY-P700031AF
• Supplier Catalog Number: HY-P700031AF
• Alternative Catalog Number: MCE-HY-P700031AF-2UG,MCE-HY-P700031AF-10UG,MCE-HY-P700031AF-50UG
• Manufacturer: MedchemExpress
• Category: Proteine/Peptide
• Alternative Names: Animal-Free BMP-8a Protein, Human (His),Human,E. coli

Product Description

BMP-8 is a pleiotropic ligand protein act as a reproductive system regulator, enriched in the ovary. BMP-8 is encoded by a pair of genes BMP8A and BMP8B, belonging to TNF-beta family[1]. BMP-8A activates the SMAD1/5/8 and the SMAD2/3 pathways in granulosa cells, to inhibit gonadotropin-induced progesterone production and steroidogenesis-related gene expression[1]. BMP-8A also involves in Nrf2 phosphorylation in cancer cells to promote survival and drug resistance[2]. BMP-8a Protein, Human is 402 a.a. with 2 glycosylation domains. Animal-Free BMP-8a Protein, Human (His) is a animal free recombinant human protein produced in E. coli cells, with 139 a.a. (A264-H402) and C-terminal His-tag.This product is for cell culture use only.

Product Properties

• Molecular Weight: Approximately 17 kDa, based on SDS-PAGE under reducing conditions.
• Purity: 98
• Formula: 353500(Gene_ID)AAP74559.1 (A264-H402)(Accession)

Application Notes

• Application Notes: MCE Product type: Recombinant Proteins