IL-7, a hematopoietic cytokine, regulates lymphocyte population and maintains lymphoid homeostasis. IL-7 binds to its receptor complex IL7RA and CSF2RG, activating kinases like JAK1 or JAK3 depending on the cell type. This triggers downstream signaling pathways, including PI3K/Akt/mTOR or JAK-STAT5, leading to various cellular responses. IL-7s interaction with IL7R and CSF2RG is crucial for its diverse effects. Animal-Free IL-7 Protein, Mouse (His) is the recombinant mouse-derived animal-FreeIL-7 protein, expressed by E. coli , with C-His labeled tag. This product is for cell culture use only.
Molecular Weight:
Approximately 16 kDa, based on SDS-PAGE under reducing conditions.
