Endothelin-1/EDN1 Protein, Human (GST),Human,E. coli
Endothelin-1/EDN1, an endothelium-derived vasoconstrictor peptide, acts as a likely ligand for G-protein coupled receptors EDNRA and EDNRB. Its binding initiates a signaling cascade in glomerular mesangial cells involving PTK2B, BCAR1, BCAR3, and GTPases RAP1 and RHOA. Furthermore, Endothelin-1/EDN1 shows binding affinity for the DEAR/FBXW7-AS1 receptor, underscoring its involvement in diverse cellular signaling and vascular regulation. Endothelin-1/EDN1 Protein, Human (GST) is the recombinant human-derived Endothelin-1/EDN1 protein, expressed by E. coli , with N-GST labeled tag.
Molecular Weight:
Approximately 28 kDa, based on SDS-PAGE under reducing conditions.
Purity:
95
Formula:
1906(Gene_ID)P05305 (C53-W73)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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