Dectin-1/CLEC7A acts as a lectin and specifically recognizes beta-1,3-linked and beta-1,6-linked glucans in bacterial and fungal cell walls. Dectin-1/CLEC7A is critical for Toll-like receptor 2 (TLR2)-mediated inflammation by recruiting SYK through its immunoreceptor tyrosine-based activation motif (ITAM), thereby activating NF-kappa-B. Dectin-1/CLEC7A Protein, Mouse (HEK293, Fc) is the recombinant mouse-derived Dectin-1/CLEC7A protein, expressed by HEK293 , with N-hFc labeled tag.
Molecular Weight:
50-65 kDa
Purity:
95.00
Formula:
56644(Gene_ID)Q6QLQ4 (G71-L244)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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