IL-22R alpha 1 and IL-10R beta together form IL20, IL22 and IL24 receptor complexes, activating different signaling pathways. Within the IL22 receptor, IL-22R alpha 1 binds to IL10RB and mediates IL22 signaling through the JAK/STAT and MAPK1/MAPK3/Akt pathways. IL-22R alpha 1 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived IL-22R alpha 1 protein, expressed by HEK293 , with C-His labeled tag.
Molecular Weight:
Approximately 38-48 kDa, based on Bis-Tris PAGE under reducing conditions.
