Integrin alpha-1/beta-1 is a receptor for laminin and collagen that recognizes the proline hydroxylation sequence GFPGER within collagen. This integrin negatively regulates EGF-stimulated cell growth and forms a heterodimeric complex with beta-1 that interacts with the small GTPase RAB21. Integrin alpha A1 beta 1 Protein, Mouse (HEK293, His) is a recombinant protein dimer complex containing mouse-derived Integrin alpha A1 beta 1 protein, expressed by HEK293 , with C-His labeled tag. Integrin alpha A1 beta 1 Protein, Mouse (HEK293, His), has molecular weight of 140-200 kDa (ITGA1) & 100-115 kDa (ITGB1), respectively.
Molecular Weight:
Approximately 140-200 kDa (ITGA1) & 100-115 kDa (ITGB1),based on SDS-PAGE under reducing conditions,due to the glycosylation.
