MCP-1/CCL2 protein activates CCR2 and induces chemotaxis and calcium ion mobilization. It attracts monocytes and basophils, not neutrophils or eosinophils. It also contributes to neuropathic pain and enhances synaptic transmission in dopamine neurons. MCP-1/CCL2 exists as a monomer or homodimer and binds to endothelial cells through proteoglycans. It interacts with TNFAIP6 via its Link domain. MCP-1/CCL2 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived MCP-1/CCL2 protein, expressed by HEK293 , with C-His labeled tag.
Molecular Weight:
Approximately 13-16 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Formula:
102135739(Gene_ID)P61274 (Q24-P99)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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