The LRIG1 protein acts as a feedback negative regulator of receptor tyrosine kinase signaling, enhancing receptor ubiquitination and promoting intracellular degradation. It interacts with various receptors, including EGFR/ERBB1, ERBB2, ERBB3, and ERBB4, through its extracellular leucine-rich repeats (LRR) and immunoglobulin-like domains. LRIG1 Protein, Cynomolgus (HEK293, His) is the recombinant cynomolgus-derived LRIG1 protein, expressed by HEK293 , with C-His labeled tag.
Molecular Weight:
Approximately 90-110 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Formula:
/(Gene_ID)A0A2K5V8J9 (A34-T792)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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