RPRD1B Protein, Human (HEK293, N-His),Human,HEK293
RPRD1B, is a necessary scaffolding protein that maintains genetic integrity by regulating resolution of R-loops at both the transcription termination and DNA double-strand break (DSB) repair levels. In endometrial cancers, RPRD1B accelerates cell cycle through up-regulating Cyclin D1, CDK4, and CDK6. In addition, RPRD1B enhancse transcription of CCND1 and promotes cell proliferation by interacting with RNA polymerase II. RPRD1B enhances the beta-CateninTCF4 transcriptional activity in response to Wnt signaling[1][2][3][4]. RPRD1B Protein, Human (HEK293, N-His) is the recombinant human-derived RPRD1B protein, expressed by HEK293 , with N-6*His labeled tag.
Molecular Weight:
37-42 kDa
Purity:
92.57
Formula:
58490(Gene_ID)AAH33629.1 (M1-D326)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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