FITC-labeled EGFR Protein, Human (HEK293, Fc),Human,HEK293
The EGFR protein is a receptor tyrosine kinase that can bind to a variety of ligands, such as EGF, TGFA, AREG, epigen, BTC, epiregulin, and HBEGF, to initiate signaling cascades that mediate cellular responses. This involves receptor dimerization, autophosphorylation and recruitment of adapter proteins such as GRB2, activating downstream pathways such as RAS-RAF-MEK-ERK, PI3-kinase-AKT, PLCgamma-PKC and STAT. FITC-labeled EGFR Protein, Human (HEK293, Fc) is the recombinant human-derived FITC-labeled EGFR protein, expressed by HEK293 , with Fc labeled tag.
Molecular Weight:
Approximately 130-150 kDa,based on SDS-PAGE under reducing conditions,due to the glycosylation.
Formula:
1956(Gene_ID)P00533-1 (L25-S645)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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