The OTUD5 protein is a deubiquitinating enzyme that crucially eliminates the innate immune response through peptidase activity on Lys-48 and Lys-63 linked polyubiquitin chains, thereby inhibiting TRAF3-mediated Type I interferon production. It acts as a regulator of neuroectodermal differentiation by cleaving ''Lys-48 linked ubiquitin chains to prevent the degradation of chromatin regulators such as ARID1A, HDAC2 and HCF1. OTUD5 Protein, Human (His, FLAG) is the recombinant human-derived OTUD5 protein, expressed by E. coli , with N-6*His, N-Flag labeled tag.
Molecular Weight:
Approximately 23.9 KDa
Purity:
94.00
Formula:
55593(Gene_ID)Q96G74 (G172-G351)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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