SMURF2 protein is an E3 ubiquitin protein ligase that interacts with SMAD7 to induce ubiquitin-dependent degradation of TGF-beta receptors and downregulate TGF-beta signaling. This interaction triggers autocatalytic degradation of SMURF2 and is antagonized by AIMP1. SMURF2 Protein, Human is the recombinant human-derived SMURF2 protein, expressed by E. coli , with tag free.
Formula:
64750(Gene_ID)Q9HAU4 (S2-E748)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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