KMT2D Protein, a histone methyltransferase, methylates histone H3 Lys-4 (H3K4), predominantly establishing H3K4me1 marks at active chromatin sites. Integral to chromatin remodeling, it functions as a coactivator for the estrogen receptor, recruited by ESR1, activating transcription. KMT2Ds role in depositing specific histone marks at genomic locations underscores its crucial involvement in modulating chromatin structure and gene expression. KMT2D Protein, Human (GST) is the recombinant human-derived KMT2D protein, expressed by E. coli , with N-GST labeled tag.
Formula:
8085(Gene_ID)O14686 (H5382-M5536)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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