LGP2 protein is a key regulator of RIGI- and IFIH1/MDA5-mediated antiviral signaling and has dual negative and positive functions affected by factors such as infected viruses and target cells. LGP2 lacks a CARD domain for independent initiation of antiviral signaling and therefore inhibits RIG-I through multiple mechanisms, including competition for RNA binding and obstruction of interaction with MAVS/IPS1. LGP2 Protein, Human (HEK293, FLAG) is the recombinant human-derived LGP2 protein, expressed by HEK293 , with C-Flag labeled tag.
Molecular Weight:
Approximately 77.6 KDa
Purity:
98
Formula:
79132(Gene_ID)Q96C10 (M1-D678)(Accession)
Application Notes:
MCE Product type: Recombinant Proteins
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